3-Ureidopropionic acid

Research use only not for human use.

Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase.

Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.

Ureidopropionic acid;Carbamoyl-b-alanine

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

——

——

462-88-4

132.12

C4H8N2O3

>98% (HPLC)

DMSO:10 mM

NC(=O)NCCC(O)=O

——

(-20℃)

With Ice Pack

≥ 2 years