3-Ureidopropionic acid

CAS No. 462-88-4

3-Ureidopropionic acid ( Ureidopropionic acid;Carbamoyl-b-alanine )

Catalog No. M19721 CAS No. 462-88-4

Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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200MG 88 In Stock
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Biological Information

  • Product Name
    3-Ureidopropionic acid
  • Note
    Research use only not for human use.
  • Brief Description
    Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase.
  • Description
    Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.
  • Synonyms
    Ureidopropionic acid;Carbamoyl-b-alanine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    462-88-4
  • Formula Weight
    132.12
  • Molecular Formula
    C4H8N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    NC(=O)NCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Brown D G Rao S Weir T L et al. Metabolomics and metabolic pathway networks from human colorectal cancers adjacent mucosa and stool[J]. Cancer & Metabolism 2016 4(1):11.
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